Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357416 | 0.82 | GAA (0.39) | KMT2AGAANPC1RAB9A | |
| SCHEMBL4024912 | 0.79 | GAA (0.37) | KMT2AGAANPC1RAB9A | |
| SCHEMBL11894311 | 0.77 | KMT2A (0.45) | KMT2AGAANPC1RAB9A | |
| SCHEMBL5476779 | 0.76 | KMT2A (0.55) | KMT2ANPC1RAB9A | |
| SCHEMBL30923385 | 0.75 | KMT2A (0.44) | KMT2AGAANPC1RAB9A | |
| SCHEMBL14357424 | 0.73 | HTR1A (0.35) | KMT2AGAANPC1RAB9A | |
| SCHEMBL22230513 | 0.72 | GAA (0.40) | GAANPC1RAB9A | |
| SCHEMBL12311449 | 0.72 | GAA (0.40) | KMT2AGAANPC1RAB9A | |
| SCHEMBL14447305 | 0.71 | GAA (0.39) | GAANPC1RAB9A | |
| SCHEMBL13621180 | 0.70 | KDM4E (0.41) | KMT2AGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |