Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 2/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952286 | 0.87 | GLP1R (0.40) | GLP1R | |
| SCHEMBL24599392 | 0.87 | GLP1R (0.40) | GLP1R | |
| SCHEMBL31323121 | 0.81 | GLP1R (0.39) | GLP1R | |
| SCHEMBL31323116 | 0.77 | GLP1R (0.38) | GLP1R | |
| SCHEMBL25595783 | 0.74 | GLP1R (0.34) | GLP1R | |
| SCHEMBL31424397 | 0.73 | GLP1R (0.41) | GLP1R | |
| SCHEMBL31692524 | 0.73 | THRB (0.32) | THRBGLP1R | |
| SCHEMBL31424405 | 0.73 | THRB (0.33) | THRBTP53MAPTGLP1R | |
| SCHEMBL20014821 | 0.73 | NR1H2 (0.33) | THRBTP53MAPTGLP1R | |
| SCHEMBL31692337 | 0.73 | THRB (0.33) | THRBTP53MAPTGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016546-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2023-02-16 | — | — | WO | disclosed |