Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 3/20 | 0.31 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047831 | 0.94 | METTL3 (0.41) | METTL3BRD4ROCK2CREBBPCYP2D6 | |
| SCHEMBL30941254 | 0.87 | BRD4 (0.36) | BRD4ROCK2CREBBPCYP2D6ADORA3 | |
| SCHEMBL30940800 | 0.84 | CHKA (0.36) | BRD4ROCK2CREBBPCYP2D6GLS | |
| SCHEMBL31618085 | 0.83 | METTL3 (0.33) | METTL3 | |
| SCHEMBL25048356 | 0.83 | METTL3 (0.33) | METTL3 | |
| SCHEMBL30941203 | 0.83 | METTL3 (0.33) | METTL3 | |
| SCHEMBL31617917 | 0.82 | HRH2 (0.31) | — | |
| SCHEMBL30941032 | 0.80 | PRMT5 (0.40) | BRD4ROCK2CREBBPCYP2D6GLS | |
| SCHEMBL25048303 | 0.80 | HTR2A (0.32) | METTL3 | |
| SCHEMBL30940742 | 0.80 | HTR2A (0.32) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |