Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 4/20 | 0.77 |
| ▸ | AHCY | P23526 | 2/20 | 0.76 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.72 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941201 | 1.00 | PRKACA (0.77) | PRKACAAHCYFTOHSP90B1ADORA3 | |
| SCHEMBL25046799 | 0.89 | AHCY (0.75) | PRKACAAHCYFTOHSP90B1ADORA3 | |
| SCHEMBL31618029 | 0.89 | AHCY (0.75) | PRKACAAHCYFTOHSP90B1ADORA3 | |
| SCHEMBL30941230 | 0.87 | AHCY (0.84) | AHCYHSP90B1ADORA3ADORA2AADORA2B | |
| SCHEMBL25047825 | 0.87 | AHCY (0.84) | AHCYHSP90B1ADORA3ADORA2AADORA2B | |
| SCHEMBL25047823 | 0.86 | AHCY (0.77) | PRKACAAHCYFTOHSP90B1ADORA3 | |
| SCHEMBL31617856 | 0.86 | AHCY (0.77) | PRKACAAHCYFTOHSP90B1ADORA3 | |
| SCHEMBL32660834 | 0.83 | PRKACA (1.00) | PRKACAAHCYHSP90B1ADORA3ADORA2A | |
| SCHEMBL25046798 | 0.83 | AHCY (0.65) | PRKACAAHCYFTOHSP90B1ADORA3 | |
| SCHEMBL31617991 | 0.83 | AHCY (0.65) | PRKACAAHCYFTOHSP90B1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |