Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047870 | 0.87 | PRMT5 (0.36) | PRMT5WDR77PIP4K2AMEN1 | |
| SCHEMBL25047915 | 0.87 | PRMT5 (0.36) | PRMT5WDR77PIP4K2AMEN1 | |
| SCHEMBL23584773 | 0.84 | PRMT5 (0.51) | PRMT5WDR77PIP4K2AMEN1 | |
| SCHEMBL25048493 | 0.81 | PRMT5 (0.37) | PRMT5WDR77PIP4K2AMEN1 | |
| SCHEMBL25047503 | 0.79 | PRMT5 (0.41) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25047937 | 0.78 | PIP4K2A (0.38) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25046651 | 0.77 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL23584505 | 0.76 | PRMT5 (0.63) | PRMT5WDR77MEN1 | |
| SCHEMBL23584587 | 0.76 | PRMT5 (0.41) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25049187 | 0.73 | PIP4K2A (0.39) | PRMT5WDR77PIP4K2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |