Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19344247 | 0.87 | PRMT5 (0.38) | PRMT5WDR77ADORA2AADORA3 | |
| SCHEMBL19667323 | 0.86 | PRMT5 (0.39) | PRMT5WDR77 | |
| SCHEMBL30207846 | 0.86 | PRMT5 (0.39) | PRMT5WDR77 | |
| SCHEMBL19667572 | 0.85 | NNMT (0.40) | PRMT5WDR77 | |
| SCHEMBL25046559 | 0.84 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL23120565 | 0.84 | PRMT5 (0.48) | PRMT5WDR77 | |
| SCHEMBL30941233 | 0.84 | PRMT5 (0.48) | PRMT5WDR77 | |
| SCHEMBL23121274 | 0.82 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL18572830 | 0.82 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL30941081 | 0.79 | PRMT5 (0.42) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |