Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940820 | 0.84 | PRMT5 (0.47) | PRMT5METTL3WDR77 | |
| SCHEMBL25049357 | 0.84 | PRMT5 (0.47) | PRMT5METTL3WDR77 | |
| SCHEMBL25047968 | 0.83 | — | — | |
| SCHEMBL25048728 | 0.82 | PRMT5 (0.39) | MEN1KMT2APRMT5NPC1RAB9A | |
| SCHEMBL25048329 | 0.79 | PRMT5 (0.40) | PRMT5NPC1RAB9APIP4K2AMETTL3 | |
| SCHEMBL25048366 | 0.77 | PRMT5 (0.37) | PRMT5PIP4K2AMETTL3WDR77 | |
| SCHEMBL25046621 | 0.76 | PIP4K2A (0.31) | PRMT5PIP4K2AWDR77 | |
| SCHEMBL25048325 | 0.75 | PRMT5 (0.37) | PRMT5PIP4K2AMETTL3WDR77 | |
| SCHEMBL25046638 | 0.74 | PRMT5 (0.38) | PRMT5PIP4K2AMETTL3WDR77 | |
| SCHEMBL25047713 | 0.73 | PRMT5 (0.41) | PRMT5PIP4K2AMETTL3WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |