Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.48 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047503 | 0.92 | PRMT5 (0.41) | PRMT5WDR77PIP4K2AYTHDC1KHK | |
| SCHEMBL25048493 | 0.90 | PRMT5 (0.37) | PRMT5WDR77PIP4K2AYTHDC1MEN1 | |
| SCHEMBL25047915 | 0.88 | PRMT5 (0.36) | PRMT5WDR77PIP4K2AYTHDC1MEN1 | |
| SCHEMBL25047870 | 0.88 | PRMT5 (0.36) | PRMT5WDR77PIP4K2AYTHDC1MEN1 | |
| SCHEMBL23584505 | 0.86 | PRMT5 (0.63) | PRMT5WDR77MEN1 | |
| SCHEMBL25047937 | 0.86 | PIP4K2A (0.38) | PRMT5WDR77PIP4K2AYTHDC1 | |
| SCHEMBL25047490 | 0.81 | PRMT5 (0.53) | PRMT5WDR77 | |
| SCHEMBL23584773 | 0.78 | PRMT5 (0.51) | PRMT5WDR77PIP4K2AMEN1ACACB | |
| SCHEMBL25047504 | 0.78 | JAK3 (0.40) | PRMT5WDR77PIP4K2A | |
| SCHEMBL23584764 | 0.78 | PRMT5 (0.63) | PRMT5WDR77MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |