Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047907 | 0.96 | GPR119 (0.39) | JAK3GPR119CNR2CNR1NAMPT | |
| SCHEMBL25048435 | 0.90 | JAK3 (0.40) | JAK3GPR119CNR2CNR1NAMPT | |
| SCHEMBL25048843 | 0.85 | GPR119 (0.39) | JAK3GPR119CNR2NAMPTPRMT5 | |
| SCHEMBL25048811 | 0.85 | GPR119 (0.40) | JAK3GPR119CNR2NAMPTPRMT5 | |
| SCHEMBL23584653 | 0.84 | PRMT5 (0.49) | JAK3GPR119CNR2CNR1PRMT5 | |
| SCHEMBL23584748 | 0.84 | GPR119 (0.40) | JAK3GPR119CNR2CNR1NAMPT | |
| SCHEMBL25047501 | 0.82 | PRMT5 (0.35) | JAK3GPR119CNR2CNR1NAMPT | |
| SCHEMBL25047914 | 0.80 | NAMPT (0.34) | JAK3GPR119CNR2CNR1NAMPT | |
| SCHEMBL25047503 | 0.79 | PRMT5 (0.41) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25047492 | 0.78 | PRMT5 (0.48) | PRMT5WDR77PIP4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |