Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | ABL2 | P42684 | 6/20 | 0.51 |
| ▸ | SRC | P12931 | 6/20 | 0.48 |
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | TEK | Q02763 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKCB | P05771 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCH | P24723 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.48 |
| ▸ | HCK | P08631 | 8/20 | 0.47 |
| ▸ | FLT3 | P36888 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046658 | 0.92 | ABL1 (0.40) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25048882 | 0.90 | ABL1 (0.39) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047506 | 0.90 | ABL1 (0.40) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047951 | 0.82 | ABL1 (0.57) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047931 | 0.77 | ABL1 (0.41) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047520 | 0.76 | METTL3 (0.47) | ABL1EGFRABL2 | |
| SCHEMBL25047965 | 0.76 | ABL1 (0.54) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25048256 | 0.74 | LCK (0.45) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25046672 | 0.74 | ABL1 (0.40) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047923 | 0.71 | ABL1 (0.41) | ABL1EGFRABL2SRCLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |