Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 20/20 | 0.32 |
| ▸ | MERTK | Q12866 | 20/20 | 0.32 |
| ▸ | FLT3 | P36888 | 16/20 | 0.32 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048279 | 0.89 | AXL (0.30) | AXLTYRO3MERTKFLT3 | |
| SCHEMBL25048244 | 0.81 | CHKA (0.33) | — | |
| SCHEMBL25048238 | 0.80 | AXL (0.33) | AXLTYRO3MERTKFLT3NUAK1 | |
| SCHEMBL25048237 | 0.80 | AXL (0.33) | AXLTYRO3MERTKFLT3NUAK1 | |
| SCHEMBL25048273 | 0.78 | ABL1 (0.33) | — | |
| SCHEMBL25048780 | 0.74 | AXL (0.31) | AXLTYRO3MERTKFLT3 | |
| SCHEMBL25048167 | 0.72 | ADCY5 (0.33) | — | |
| SCHEMBL25048282 | 0.71 | AXL (0.32) | AXLTYRO3MERTKFLT3 | |
| SCHEMBL25048778 | 0.70 | AXL (0.34) | AXLTYRO3MERTKFLT3NUAK1 | |
| SCHEMBL25047923 | 0.68 | ABL1 (0.41) | TYRO3MERTKFLT3NTRK1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |