Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ABL2 | P42684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047686 | 0.81 | AXL (0.32) | — | |
| SCHEMBL25046747 | 0.78 | C1S (0.33) | FGFR1FGFR4ABL1EGFRABL2 | |
| SCHEMBL25048279 | 0.76 | AXL (0.30) | — | |
| SCHEMBL25048273 | 0.72 | ABL1 (0.33) | ABL1EGFRABL2 | |
| SCHEMBL25049073 | 0.71 | ABL1 (0.41) | ABL1EGFRABL2 | |
| SCHEMBL25047923 | 0.71 | ABL1 (0.41) | FGFR1FGFR4ABL1EGFRABL2 | |
| SCHEMBL25049217 | 0.70 | C1S (0.36) | CHKAFGFR1FGFR4ABL1EGFR | |
| SCHEMBL25046672 | 0.69 | ABL1 (0.40) | FGFR1FGFR4ABL1EGFRABL2 | |
| SCHEMBL25048167 | 0.69 | ADCY5 (0.33) | ABL1EGFRABL2 | |
| SCHEMBL25047634 | 0.67 | ADK (0.39) | CHKAFGFR1FGFR4ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |