Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049352 | 0.92 | PRMT5 (0.42) | PRMT5METTL3FDFT1CYP2D6WDR77 | |
| SCHEMBL25048777 | 0.88 | PRMT5 (0.41) | PRMT5METTL3FDFT1WDR77 | |
| SCHEMBL25048298 | 0.86 | PRMT5 (0.42) | PRMT5METTL3WDR77 | |
| SCHEMBL25047841 | 0.86 | MEN1 (0.37) | PRMT5FDFT1CYP2D6 | |
| SCHEMBL25048701 | 0.82 | PRMT5 (0.40) | PRMT5 | |
| SCHEMBL31618056 | 0.80 | PRMT5 (0.43) | PRMT5METTL3WDR77 | |
| SCHEMBL31618015 | 0.78 | PRMT5 (0.44) | PRMT5METTL3WDR77 | |
| SCHEMBL25046813 | 0.77 | PRMT5 (0.47) | PRMT5METTL3WDR77 | |
| SCHEMBL25048258 | 0.76 | PRMT5 (0.49) | PRMT5METTL3WDR77 | |
| SCHEMBL31618087 | 0.76 | PRMT5 (0.49) | PRMT5METTL3WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |