Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 11/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048777 | 0.94 | PRMT5 (0.41) | PRMT5 | |
| SCHEMBL25047809 | 0.91 | PRMT5 (0.41) | PRMT5FFAR1 | |
| SCHEMBL31618039 | 0.91 | PRMT5 (0.41) | PRMT5FFAR1 | |
| SCHEMBL25048298 | 0.90 | PRMT5 (0.42) | PRMT5 | |
| SCHEMBL31618056 | 0.85 | PRMT5 (0.43) | PRMT5 | |
| SCHEMBL25048705 | 0.85 | CCR8 (0.40) | FFAR1KDM4EMAPK1 | |
| SCHEMBL25047461 | 0.82 | PRMT5 (0.37) | PRMT5 | |
| SCHEMBL25047840 | 0.82 | PRMT5 (0.40) | PRMT5 | |
| SCHEMBL31618015 | 0.81 | PRMT5 (0.44) | PRMT5 | |
| SCHEMBL25048301 | 0.75 | CCR8 (0.40) | PRMT5FFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |