Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 12/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047427 | 0.87 | PIP4K2A (0.38) | PRMT5WDR77ADCY5 | |
| SCHEMBL25048759 | 0.83 | ADCY5 (0.42) | PRMT5WDR77ADCY5ADKMETTL3 | |
| SCHEMBL19714822 | 0.78 | ADCY5 (0.49) | PRMT5WDR77ADCY5ADKMETTL3 | |
| SCHEMBL18571704 | 0.77 | MEN1 (0.41) | PRMT5WDR77ADKMETTL3MEN1 | |
| SCHEMBL19714842 | 0.77 | ADCY5 (0.48) | PRMT5WDR77ADCY5ADK | |
| SCHEMBL19714888 | 0.76 | ADCY5 (0.67) | PRMT5WDR77ADCY5ADK | |
| SCHEMBL14447403 | 0.75 | MEN1 (0.43) | PRMT5WDR77ADKMEN1 | |
| SCHEMBL25047869 | 0.75 | PRMT5 (0.34) | PRMT5WDR77ADCY5ADKMETTL3 | |
| SCHEMBL23584600 | 0.72 | ADCY5 (0.47) | PRMT5WDR77ADCY5ADKMETTL3 | |
| SCHEMBL19344041 | 0.72 | ADCY5 (0.47) | PRMT5WDR77ADCY5ADKMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |