Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | HCK | P08631 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049134 | 0.83 | PIP4K2A (0.46) | PRMT5WDR77PIK3CDABL1EGFR | |
| SCHEMBL10293822 | 0.81 | PIP4K2A (0.49) | PRMT5WDR77PIP4K2A | |
| SCHEMBL10293819 | 0.81 | MEN1 (0.47) | MEN1ADKPRMT5WDR77ADORA2A | |
| SCHEMBL25047848 | 0.81 | ADK (0.50) | MEN1ADKPRMT5WDR77ADORA2A | |
| SCHEMBL10242174 | 0.81 | ADORA2A (0.56) | MEN1ADKPRMT5WDR77ABL1 | |
| SCHEMBL19344041 | 0.80 | ADCY5 (0.47) | MEN1ADKPRMT5WDR77ABL1 | |
| SCHEMBL10236925 | 0.80 | ADCY5 (0.47) | MEN1ADKPRMT5WDR77ABL1 | |
| SCHEMBL23584600 | 0.80 | ADCY5 (0.47) | MEN1ADKPRMT5WDR77ABL1 | |
| SCHEMBL18571704 | 0.80 | MEN1 (0.41) | MEN1ADKPRMT5WDR77ADORA2A | |
| SCHEMBL25048759 | 0.80 | ADCY5 (0.42) | MEN1ADKPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092213-A2 | INHIBITORS OF E1 ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | disclosed |