Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 16/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 11/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940791 | 1.00 | PRMT5 (0.39) | PRMT5WDR77METTL3NNMTDOT1L | |
| SCHEMBL25048837 | 0.83 | PRMT5 (0.41) | PRMT5WDR77METTL3 | |
| SCHEMBL30940916 | 0.82 | PRMT5 (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL30941564 | 0.82 | PRMT5 (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL25048883 | 0.82 | PRMT5 (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL25048831 | 0.78 | PRMT5 (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL30941073 | 0.78 | PRMT5 (0.46) | PRMT5WDR77METTL3 | |
| SCHEMBL25047812 | 0.75 | ADORA3 (0.42) | PRMT5WDR77 | |
| SCHEMBL30941021 | 0.75 | PRMT5 (0.43) | PRMT5WDR77METTL3 | |
| SCHEMBL25047936 | 0.71 | PRMT5 (0.46) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |