Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 9/20 | 0.36 |
| ▸ | GRM5 | P41594 | 9/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048817 | 0.92 | TNK2 (0.38) | GRM1GRM5TNK2JAK1CDK7 | |
| SCHEMBL25048539 | 0.81 | GPR119 (0.42) | SRCEGFR | |
| SCHEMBL25048941 | 0.79 | SRC (0.38) | TNK2SRCEGFR | |
| SCHEMBL25048063 | 0.75 | SRC (0.40) | SRCEGFR | |
| SCHEMBL31651865 | 0.74 | PDK4 (0.48) | GRM1GRM5TNK2JAK1CDK7 | |
| SCHEMBL25046687 | 0.72 | SRC (0.42) | SRCEGFR | |
| SCHEMBL25048816 | 0.72 | TNK2 (0.33) | GRM1GRM5TNK2 | |
| SCHEMBL30940882 | 0.71 | GRM5 (0.32) | GRM1GRM5 | |
| SCHEMBL19243936 | 0.71 | SRC (0.41) | SRCEGFR | |
| SCHEMBL25047547 | 0.70 | TNK2 (0.48) | GRM1GRM5TNK2JAK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |