Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047759 | 0.91 | PRMT5 (0.40) | PRMT5WDR77METTL3 | |
| SCHEMBL25048286 | 0.84 | PRMT5 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL25047713 | 0.82 | PRMT5 (0.41) | PRMT5WDR77METTL3 | |
| SCHEMBL25046631 | 0.78 | PRMT5 (0.40) | PRMT5WDR77METTL3NPY5R | |
| SCHEMBL25047385 | 0.77 | NNMT (0.36) | PRMT5WDR77METTL3NPY5R | |
| SCHEMBL25046815 | 0.75 | PRMT5 (0.52) | PRMT5WDR77METTL3 | |
| SCHEMBL30941466 | 0.75 | PRMT5 (0.52) | PRMT5WDR77METTL3 | |
| SCHEMBL25048285 | 0.73 | MEN1 (0.41) | PRMT5WDR77 | |
| SCHEMBL23892527 | 0.71 | PRMT5 (0.53) | PRMT5WDR77METTL3 | |
| SCHEMBL25047393 | 0.71 | PRMT5 (0.40) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |