Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 13/20 | 0.64 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284113 | 0.85 | AGER (0.60) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1283226 | 0.85 | AGER (0.64) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1615394 | 0.84 | AGER (0.65) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1283410 | 0.84 | AGER (0.65) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1283339 | 0.83 | AGER (0.63) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1283911 | 0.83 | AGER (0.63) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1283433 | 0.83 | AGER (0.63) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1282986 | 0.82 | AGER (0.60) | AGERATP4AATP4BIKBKBHRH3 | |
| SCHEMBL1283662 | 0.82 | AGER (0.67) | AGERATP4AATP4BHRH3 | |
| SCHEMBL1283607 | 0.82 | AGER (0.59) | AGERATP4AATP4BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482931-B1 | MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE | TRANSTECH PHARMA INC (US) | 2011-10-19 | — | — | EP | disclosed |