Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | STAT6 | P42226 | 2/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047878 | 0.90 | ADK (0.61) | ADKHIF1ATP53STAT6DOT1L | |
| SCHEMBL17816344 | 0.87 | ADK (0.78) | ADKHIF1ATP53STAT6SLC29A1 | |
| SCHEMBL17800832 | 0.86 | ADK (1.00) | ADKHIF1ATP53STAT6SLC29A1 | |
| SCHEMBL31617931 | 0.86 | ADK (1.00) | ADKHIF1ATP53STAT6SLC29A1 | |
| SCHEMBL16330689 | 0.85 | ADK (0.72) | ADKHIF1ATP53STAT6SLC29A1 | |
| SCHEMBL17800864 | 0.83 | ADK (0.72) | ADKHIF1ATP53STAT6SLC29A1 | |
| SCHEMBL16330688 | 0.83 | HIF1A (0.76) | ADKHIF1ATP53STAT6SLC29A1 | |
| SCHEMBL17800859 | 0.82 | ADK (0.80) | ADK | |
| SCHEMBL17800851 | 0.80 | ADK (0.67) | ADKHIF1ATP53STAT6ALDH1A1 | |
| SCHEMBL17800845 | 0.79 | ADK (0.66) | ADKHIF1ATP53STAT6SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |