Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12297786 | 0.92 | HTR2C (0.42) | HTR2CALDH1A1TSHRCHRM1DRD2 | |
| SCHEMBL22870503 | 0.86 | HTR2C (0.46) | HTR2CALDH1A1TSHRPDGFRBPDGFRA | |
| SCHEMBL17514730 | 0.86 | ALDH1A1 (0.50) | HTR2CALDH1A1TSHRPDGFRBPDGFRA | |
| SCHEMBL7723674 | 0.84 | ALDH1A1 (0.48) | HTR2CALDH1A1TSHRPDGFRBPDGFRA | |
| SCHEMBL20789976 | 0.82 | ALDH1A1 (0.50) | HTR2CALDH1A1TSHRPDGFRBPDGFRA | |
| SCHEMBL17595118 | 0.80 | CHRM1 (0.38) | HTR2CALDH1A1CHRM1MEN1KMT2A | |
| SCHEMBL12297790 | 0.80 | HTR2C (0.50) | HTR2CALDH1A1TSHRDRD2 | |
| SCHEMBL1613815 | 0.78 | ALDH1A1 (0.55) | HTR2CALDH1A1TSHRDRD2MEN1 | |
| SCHEMBL25382518 | 0.78 | MAPT (0.42) | DRD2MEN1KMT2AMAPTPTGDR2 | |
| SCHEMBL25046750 | 0.77 | PDE4A (0.45) | HTR2CALDH1A1CHRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |