Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 16/20 | 0.43 |
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | ABL1 | P00519 | 6/20 | 0.43 |
| ▸ | ABL2 | P42684 | 5/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | NPM1 | P06748 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941267 | 0.81 | ADK (0.54) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25049361 | 0.81 | ADK (0.54) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25048564 | 0.80 | RIPK2 (0.44) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25048035 | 0.77 | ADK (0.47) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25048562 | 0.75 | ADK (0.44) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25047634 | 0.73 | ADK (0.39) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25046627 | 0.72 | ADK (0.45) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25046789 | 0.70 | ADK (0.55) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL30941042 | 0.70 | ADK (0.55) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25048027 | 0.70 | ADK (0.42) | ADKSRCEGFRABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |