⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048544 | 0.83 | PRMT5 (0.39) | — | |
| SCHEMBL25049147 | 0.79 | IGF1R (0.30) | — | |
| SCHEMBL30940748 | 0.73 | PRMT5 (0.39) | — | |
| SCHEMBL25046817 | 0.73 | PRMT5 (0.39) | — | |
| SCHEMBL25049109 | 0.72 | — | — | |
| SCHEMBL30940844 | 0.72 | PRMT5 (0.40) | — | |
| SCHEMBL25048867 | 0.72 | PRMT5 (0.40) | — | |
| SCHEMBL25049071 | 0.71 | CA2 (0.38) | — | |
| SCHEMBL25048890 | 0.70 | PRMT5 (0.39) | — | |
| SCHEMBL30941315 | 0.70 | PRMT5 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |