Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.33 |
| ▸ | NNMT | P40261 | 9/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941334 | 1.00 | PRMT5 (0.33) | PRMT5WDR77NNMT | |
| SCHEMBL25048173 | 0.90 | — | — | |
| SCHEMBL30941064 | 0.90 | — | — | |
| SCHEMBL31618021 | 0.88 | BACE1 (0.35) | PRMT5WDR77NNMT | |
| SCHEMBL25047426 | 0.85 | PRMT5 (0.35) | PRMT5WDR77NNMT | |
| SCHEMBL25046608 | 0.84 | NNMT (0.36) | PRMT5WDR77NNMT | |
| SCHEMBL25047832 | 0.81 | NNMT (0.42) | PRMT5WDR77NNMT | |
| SCHEMBL31618096 | 0.81 | MCL1 (0.31) | — | |
| SCHEMBL25046742 | 0.81 | MCL1 (0.31) | — | |
| SCHEMBL25049250 | 0.79 | BACE1 (0.36) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |