SCHEMBL25049541

SCHEMBL25049541

CCC(F)(F)CCCNC

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.40
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31346201 0.98 EPHX1 (0.39) EPHX1
SCHEMBL20182486 0.84
SCHEMBL470955 0.76
SCHEMBL30697411 0.75 CES2 (0.36)
SCHEMBL23132310 0.75 EPHX1 (0.36) EPHX1
Hydrochloric Acid SCHEMBL9358975 0.74 EPHX1 (0.38) EPHX1SIGMAR1
SCHEMBL25600758 0.74
SCHEMBL8366370 0.73
SCHEMBL18685898 0.72 EPHX1 (0.42) EPHX1SIGMAR1
SCHEMBL16925357 0.70 CES2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023018810-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2023-02-16 WO disclosed