Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499340 | 1.00 | FFAR1 (0.47) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3653937 | 0.84 | FFAR1 (0.56) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3654240 | 0.84 | FFAR1 (0.56) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2505637 | 0.82 | KMT2A (0.49) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2505240 | 0.82 | KMT2A (0.49) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3658273 | 0.81 | KMT2A (0.47) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3658813 | 0.81 | KMT2A (0.47) | FFAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2495826 | 0.79 | HCAR1 (0.35) | FFAR1 | |
| SCHEMBL2503182 | 0.79 | HCAR1 (0.35) | FFAR1 | |
| SCHEMBL2505236 | 0.75 | FFAR1 (0.47) | FFAR1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |