Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306200 | 1.00 | HTR2C (0.49) | HTR2CHTR2AKDM1AKDM1BHTR2B | |
| SCHEMBL18782895 | 0.86 | HTR2C (0.44) | HTR2CHTR2AHTR2BCHRNB2CHRNB4 | |
| SCHEMBL11034439 | 0.81 | HTR2C (0.49) | HTR2CHTR2AHTR2B | |
| SCHEMBL4102416 | 0.81 | HTR2C (0.46) | HTR2CHTR2AKDM1AKDM1BHTR2B | |
| SCHEMBL18950390 | 0.81 | HTR2C (0.46) | HTR2CHTR2AKDM1AKDM1BHTR2B | |
| SCHEMBL25053363 | 0.81 | HTR2C (0.46) | HTR2CHTR2AKDM1AKDM1BHTR2B | |
| SCHEMBL4294177 | 0.80 | KDM1A (0.44) | KDM1AKDM1BJAK2NTRK1 | |
| SCHEMBL20016164 | 0.80 | KDM1A (0.44) | KDM1AKDM1BJAK2NTRK1 | |
| SCHEMBL21400027 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4JAK2 | |
| SCHEMBL21400030 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |