Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479680 | 0.76 | TSHR (0.37) | TSHRTRPA1PRCPNPSR1USP2 | |
| SCHEMBL8535706 | 0.76 | TRPA1 (0.50) | TSHRTRPA1PRCPNPSR1MAPK1 | |
| SCHEMBL26984276 | 0.76 | TRPA1 (0.50) | TSHRTRPA1PRCPNPSR1MAPK1 | |
| SCHEMBL2706482 | 0.76 | TRPA1 (0.50) | TSHRTRPA1PRCPNPSR1MAPK1 | |
| SCHEMBL2705811 | 0.76 | TRPA1 (0.50) | TSHRTRPA1PRCPNPSR1MAPK1 | |
| SCHEMBL20449165 | 0.75 | KDM1A (0.41) | TSHRTRPA1PRCPALDH1A1KDM1A | |
| SCHEMBL13627524 | 0.75 | KDM1A (0.41) | TSHRTRPA1PRCPALDH1A1KDM1A | |
| Hydrochloric Acid SCHEMBL27077286 | 0.74 | TRPA1 (0.49) | TSHRTRPA1PRCPNPSR1MAPK1 | |
| SCHEMBL3402260 | 0.73 | KDM1A (0.40) | TSHRPRCPMEN1KMT2AKDM1A | |
| SCHEMBL20528510 | 0.73 | KDM1A (0.40) | TSHRPRCPMEN1KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |