SCHEMBL250540

SCHEMBL250540

C[Si](C)(C)O[Si](O[SiH2]c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11094520 0.87
SCHEMBL7649037 0.83
SCHEMBL18759723 0.81 ESR1 (0.31) ESR1ESR2
SCHEMBL31288439 0.81 ESR1 (0.31) ESR1ESR2
SCHEMBL21114725 0.81 ESR1 (0.32) ESR1ESR2
SCHEMBL1657410 0.80
SCHEMBL94228 0.80 ESR1 (0.39) ESR1ESR2
SCHEMBL8642322 0.79 ESR1 (0.32) ESR1ESR2
SCHEMBL31536438 0.79
SCHEMBL2360759 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3983 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380541-A1 PERSONAL CARE COMPOSITIONS BASED ON AMINOACIDS AND SKIN PENETRATION ENHANCER Colgate-Palmolive Company (US) 2024-06-12 EP claimed
US-20230181437-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-06-15 US claimed
WO-2023039220-A1 PERSONAL CARE COMPOSITIONS BASED ON AMINOACIDS AND SKIN PENETRATION ENHANCER COLGATE-PALMOLIVE COMPANY (US) 2023-03-16 WO claimed
CN-115315246-A Solid composition in the form of a water-in-oil emulsion 莱雅公司 2022-11-08 CN claimed
US-11389381-B2 Cosmetic solid composition comprising a non volatile hydrocarbonated oil, waxes and a high content from non volatile phenylated silicone oil L'OREAL (FR) 2022-07-19 US claimed
EP-3883653-A1 COSMETIC MAKE-UP COMPOSITION WITH LONG-LASTING SKIN-PERFECTING EFFECT L V M H RECHERCHE (FR) 2021-09-29 EP claimed
US-20210251856-A1 COMPOSITION COMPRISING A SATURATED FATTY ALCOHOL, AT LEAST ONE FATTY-CHAIN ANIONIC SURFACTANT, A POLYOL AND AT LEAST ONE SILICONE OIL L'OREAL (FR) 2021-08-19 US claimed
CN-113038991-A Cosmetic composition with long-lasting skin beautifying effect LVMH研究公司 2021-06-25 CN claimed
WO-2021120084-A1 SOLID COMPOSITION IN THE FORM OF WATER-IN-OIL EMULSION L'OREAL (FR) 2021-06-24 WO claimed
EP-3813954-A1 COMPOSITION COMPRISING A SATURATED FATTY ALCOHOL, AT LEAST ONE FATTY-CHAIN ANIONIC SURFACTANT, A POLYOL AND AT LEAST ONE SILICONE OIL L'OREAL (FR) 2021-05-05 EP claimed
US-6180123-B1 FOR CARE AND/OR MAKE-UP OF SKIN, HUMAN FACE AND HUMAN BODY, MUCOUS MEMBRANES SUCH AS LIPS AND INSIDE OF LOWER EYELIDS, OR THE SUPERFICIAL BODY GROWTHS SUCH AS EYELASHES, EYEBROWS, NAILS AND HAIR L'OREAL (FR) 2001-01-30 US claimed
EP-1064930-A1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane L'OREAL (FR) 2001-01-03 EP claimed
EP-1053742-A1 Anhydrous skin care or make-up compositions containing fibres and polyols L'OREAL (FR) 2000-11-22 EP claimed
EP-1008339-A1 Cosmetic composition containing an association of acexamic acid and polyols L'OREAL (FR) 2000-06-14 EP claimed
EP-0997141-A1 COSMETIC COMPOSITION CONTAINING AT LEAST ONE AMORPHOUS POLYCYCLOOLEFINE OR A MIXTURE AND THEIR USE L'OREAL (FR) 2000-05-03 EP claimed
US-6042842-A IN MAKE UPS, LIPSTICKS, EYELINER, MASCERA; FOR PROTECTING SKIN, LIPS OR KERATINOUS FIBRES AGAINST THE DAMAGING EFFECTS OF FREE RADICALS OR COMBATING CUTANEOUS SIGNS OF AGEING L'OREAL S.A. (FR) 2000-03-28 US claimed
WO-2000000163-A1 ANTIBODIES AND COMPOSITIONS FOR TOPICAL USE CONTAINING SAME L'OREAL (FR) 2000-01-06 WO claimed
EP-0951897-A2 Topical composition containing an olefinic copolymer with controlled crystallisation L'OREAL (FR) 1999-10-27 EP claimed
US-5961998-A Glossy composition containing aromatic oils thickened by a polysaccharide ether L'OREAL (FR) 1999-10-05 US claimed
EP-0891767-A1 Glossy composition containing aromatic oils thickened with an alkylether of a polysaccharide L'OREAL (FR) 1999-01-20 EP claimed