SCHEMBL94228

SCHEMBL94228

C[Si](C)(C)O[Si](O[Si](C)(C)C)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
AGXT P21549 1/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
GPR3 P46089 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992173 0.97 ESR1 (0.38) ESR1ESR2NR1H2NR1H3AGXT
SCHEMBL16521498 0.97 ESR1 (0.38) ESR1ESR2NR1H2NR1H3AGXT
SCHEMBL12458287 0.91 ESR1 (0.34) ESR1ESR2GPR3
SCHEMBL93978 0.91 ESR1 (0.34) ESR1ESR2
SCHEMBL17123467 0.91 ESR1 (0.34) ESR1ESR2
SCHEMBL18179380 0.91 ESR1 (0.34) ESR1ESR2
SCHEMBL26973343 0.89 ESR1 (0.33) ESR1ESR2
SCHEMBL19999251 0.89 ESR1 (0.33) ESR1ESR2
SCHEMBL26427810 0.89 ESR1 (0.38) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL30003313 0.89 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0037266-A2 Method and apparatus for controlling the temperature of or indicating the presence of a material by means of a waveguide, heat activatable articles incorporating waveguides; and novel waveguides and a method of making such waveguides RAYCHEM CORPORATION (a California corporation) (US) 1981-10-07 EP claimed
JP-5051390-A None JP disclosed
WO-2023112847-A1 ORGANOSILOXANE-BASED HYDROGEN STORAGE COMPOSITION 国立大学法人東京大学 2023-06-22 WO disclosed
US-11384170-B2 Process for the preparation of solid catalyst BOREALIS AG (AT) 2022-07-12 US disclosed
US-20210179744-A1 PROCESS FOR THE PREPARATION OF SOLID CATALYST BOREALIS AG (AT) 2021-06-17 US disclosed
CN-108727979-B Coating composition and coating material and coating layer and silicon oxide coating layer and article having the coating layer and method for forming coating layer on substrate surface 广东美的厨房电器制造有限公司 2021-05-07 CN disclosed
CN-109096915-B Coating composition and coating material and coating layer and silicon oxide coating layer and article having the coating layer and method for forming coating layer on substrate surface 广东美的厨房电器制造有限公司 2021-04-20 CN disclosed
CN-111757896-A Process for preparing solid catalyst 博里利斯股份公司 2020-10-09 CN disclosed
US-9909221-B2 Controllable reductive method for synthesizing metal-containing particles UT-BATTELLE, LLC (US) 2018-03-06 US disclosed
EP-3063185-B9 SOLID SINGLE SITE CATALYSTS WITH HIGH POLYMERISATION ACTIVITY BOREALIS AG (AT) 2017-11-15 EP disclosed
JP-H0551390-A FLUOROALKYL GROUP-CONTAINING ORGANIC SILICON COMPOUND AND ITS PRODUCTION NIPPON OIL & FATS CO LTD 1993-03-02 JP disclosed
US-5013715-A Pasty organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-05-07 US disclosed
US-4824982-A Method for the cleavage of organic siloxanes, and products and applications thereof HUELS TROISDORF AG (DE) 1989-04-25 US disclosed
EP-0115772-B1 PROCESS FOR THE SPLITTING OF ORGANOSILOXANES AND RESULTING PRODUCTS AND THEIR APPLICATIONS HÜLS AKTIENGESELLSCHAFT (DE) 1989-02-15 EP disclosed
US-4505542-A Thermostatic fiber optic waveguides RAYCHEM CORPORATION (US) 1985-03-19 US disclosed
EP-0115772-A2 Process for the splitting of organosiloxanes and resulting products and their applications HÜLS AKTIENGESELLSCHAFT (DE) 1984-08-15 EP disclosed
US-4417782-A Fiber optic temperature sensing RAYCHEM CORPORATION (US) 1983-11-29 US disclosed
US-4373768-A Thermostatic fiber optic waveguides RAYCHEM CORPORATION (US) 1983-02-15 US disclosed
EP-0037266-A2 Method and apparatus for controlling the temperature of or indicating the presence of a material by means of a waveguide, heat activatable articles incorporating waveguides; and novel waveguides and a method of making such waveguides RAYCHEM CORPORATION (a California corporation) (US) 1981-10-07 EP disclosed
US-4113760-A ACTIVATED CHARCOAL CATALYST WACKER-CHEMIE GMBH (DE) 1978-09-12 US disclosed