Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2505650 | 1.00 | CES2 (0.54) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL3660864 | 0.87 | CES2 (0.56) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL3660861 | 0.87 | CES2 (0.56) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL15280988 | 0.86 | CES2 (0.49) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL29867506 | 0.84 | NPC1 (0.48) | PARP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL3651297 | 0.83 | CES1 (0.46) | CES2CES1RAB9ANPC1MEN1 | |
| SCHEMBL17755036 | 0.80 | CES2 (0.59) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL4012777 | 0.80 | CES2 (0.59) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL4012772 | 0.80 | CES2 (0.59) | CES2CES1PARP1RAB9ANPC1 | |
| SCHEMBL13183360 | 0.78 | CES2 (0.53) | CES2CES1PARP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |