SCHEMBL25057

SCHEMBL25057

COC(C)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469539 1.00
SCHEMBL2222863 1.00
Hydrochloric Acid SCHEMBL3240951 0.97
Methylene Chloride SCHEMBL28156285 0.89 EPHX1 (0.32)
SCHEMBL2449252 0.78 LMNA (0.35)
SCHEMBL10363207 0.75
Isobutyramide SCHEMBL28181390 0.73
SCHEMBL6843879 0.73 SMN1; SMN2 (0.33)
SCHEMBL24304565 0.73
SCHEMBL9353672 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117500779-B Method for obtaining biogenic N-vinylformamide 爱森集团 2025-05-06 CN claimed
CN-113227043-B Composition for producing N-vinylcarboxylic acid amide 株式会社力森诺科 2024-05-07 CN claimed
CN-108701171-B Pharmacophores, compounds and methods having application in the treatment of cancer by inhibition of CYP17a1 and CYP19a1 马古苏托科技大学 2022-06-10 CN claimed
CN-113227043-A Composition for producing N-vinylcarboxylic acid amide 昭和电工株式会社 2021-08-06 CN claimed
CN-111484456-A Refining process of 5-methoxy-4, 6-dichloropyrimidine 常熟市金申医化制品有限责任公司 2020-08-04 CN claimed
US-8426447-B2 Spiro-tricyclic ring compounds as beta-secretase modulators and methods of use AMGEN INC. (US) 2013-04-23 US claimed
EP-2571880-A1 PYRROLO [2, 3 - B]PYRAZINE - 7 - CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS F.HOFFMANN-LA ROCHE AG (CH) 2013-03-27 EP claimed
EP-2566855-A1 2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS F. Hoffmann-La Roche AG (CH) 2013-03-13 EP claimed
EP-2516423-A1 THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI Bayer CropScience AG (DE) 2012-10-31 EP claimed
WO-2011138293-A1 2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2011-11-10 WO claimed
WO-2008005338-A1 MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2008-01-10 WO claimed
EP-1638942-A1 CIS-2,4,5-TRIARYL-IMIDAZOLINES F. HOFFMANN-LA ROCHE AG (CH) 2006-03-29 EP claimed
US-20050124683-A1 HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis AGOURON PHARMACEUTICALS, INC. 2005-06-09 US claimed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 US claimed
WO-2005026114-A1 HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME AND THEIR PHARMACEUTICAL USES PFIZER INC. (US) 2005-03-24 WO claimed
WO-2005003097-A1 CIS-2,4,5-TRIARYL-IMIDAZOLINES F. HOFFMANN-LA ROCHE AG (CH) 2005-01-13 WO claimed
US-6423711-B1 USEFUL IN DIAGNOSIS AND THERAPY OF ANXIETY, DOWN SYNDROME, SLEEP, COGNITIVE AND SEIZURE DISORDERS, AND OVERDOSE WITH BENZODIAZEPINE DRUGS AND FOR ENHANCEMENT OF ALERTNESS NEUROGEN CORPORATION 2002-07-23 US claimed
EP-0827988-B1 Mixtures of disperse dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-12-05 EP claimed
US-5910624-A DYEING HYDROPHOBIC FIBERS; COLORFASTNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-06-08 US claimed
EP-0827988-A1 Mixtures of disperse dyes DyStar Textilfarben GmbH &amp; Co. Deutschland KG (DE) 1998-03-11 EP claimed