Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30194813 | 1.00 | MAPT (0.60) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL25058852 | 0.87 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL22613516 | 0.79 | MAPT (0.44) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29561939 | 0.78 | MAPT (0.43) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL21315440 | 0.78 | MAPT (0.43) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL13296055 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL25058843 | 0.77 | MAPT (0.46) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL23053040 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL25058842 | 0.75 | IDO1 (0.54) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11980490 | 0.74 | IDO1 (0.55) | MAPTALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219632-A2 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3759171-B9 | AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2023-05-24 | — | — | EP | disclosed |
| EP-3759171-B1 | AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2023-02-22 | — | — | EP | disclosed |