Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 19/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26328570 | 0.88 | ACACB (0.34) | ACACB | |
| SCHEMBL18591835 | 0.88 | ACACB (0.34) | ACACB | |
| SCHEMBL21214847 | 0.86 | GRM5 (0.34) | ACACB | |
| SCHEMBL18551308 | 0.85 | ACACB (0.40) | ACACB | |
| SCHEMBL18551220 | 0.84 | ACACB (0.34) | ACACBALDH1A1 | |
| SCHEMBL24920843 | 0.82 | ACACB (0.33) | ACACB | |
| SCHEMBL21664699 | 0.80 | ACACB (0.41) | ACACB | |
| SCHEMBL20133165 | 0.79 | ACACB (0.38) | ACACB | |
| SCHEMBL21906682 | 0.76 | ACACB (0.36) | ACACB | |
| SCHEMBL26748745 | 0.73 | ACACB (0.39) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-B1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS INC (US) | 2023-02-22 | — | — | EP | disclosed |