SCHEMBL25061501

SCHEMBL25061501

COCC1(C(=O)OC)CC(C(C)(C)C)=NO1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.35
F2 P00734 2/20 0.32
F10 P00742 2/20 0.32
PRSS1 P07477 2/20 0.32
ITGB1 P05556 1/20 0.30
ITGA4 P13612 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25061644 0.87 CRBN (0.33) CRBN
SCHEMBL25061613 0.87 CRBN (0.33) CRBN
SCHEMBL25061473 0.87 CRBN (0.35) CRBNITGB1ITGA4
SCHEMBL17000140 0.78 TP53 (0.31) F2F10PRSS1
SCHEMBL25061530 0.76 CRBN (0.33) CRBNF2F10PRSS1
SCHEMBL25061688 0.76 LMNA (0.34) CRBN
Hydrochloric Acid SCHEMBL25402145 0.75 F2 (0.31) F2F10PRSS1
SCHEMBL25061595 0.74 CRBN (0.37) CRBN
SCHEMBL25061497 0.73 CRBN (0.35) CRBN
SCHEMBL25061646 0.73 CRBN (0.36) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230053699-A1 SUBSTITUTED-ISOXAZOLINE-CONTAINING AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2023-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230053699-A1 SUBSTITUTED-ISOXAZOLINE-CONTAINING AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF CYP4X1, CYP4F11, CBR3 CRBN 1907/4885F2 1404/4885F10 2779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.