SCHEMBL25064299

SCHEMBL25064299

CNC(C)(C)CC(C)(C)CNC(=O)C(C)(C)CC(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22631759 0.95
SCHEMBL22758126 0.85 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10
SCHEMBL14191687 0.80 SMN1; SMN2 (0.31) SMN1; SMN2HSD17B10
SCHEMBL26992417 0.77 SMN1; SMN2 (0.33) SMN1; SMN2HSD17B10
SCHEMBL25064237 0.76 POLB (0.37)
SCHEMBL16592069 0.74 NAMPT (0.30)
SCHEMBL18873139 0.72
SCHEMBL19710059 0.72 SMN1; SMN2 (0.32) SMN1; SMN2HSD17B10
SCHEMBL20172542 0.71 LMNA (0.30)
SCHEMBL21946461 0.71 KDM4C (0.42) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230059250-A1 Anti-CD37 Antibody-Maytansine Conjugates and Methods of Use Thereof ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2023-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230059250-A1 Anti-CD37 Antibody-Maytansine Conjugates and Methods of Use Thereof SIGLEC7, FUT7, CD2 SMN1; SMN2 3471/4885HSD17B10 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.