SCHEMBL2506447

SCHEMBL2506447

CC1(C)CCC=C1c1cc(COc2cccc([C@@H](CC(=O)O)C3(C)CC3)c2)ccc1-c1cc(C(F)(F)F)ccc1F

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2498612 1.00 FFAR1 (0.64) FFAR1
SCHEMBL2499120 0.91 FFAR1 (0.68) FFAR1
SCHEMBL2499973 0.91 FFAR1 (0.68) FFAR1
SCHEMBL2496980 0.90 FFAR1 (0.66) FFAR1
SCHEMBL2494906 0.90 FFAR1 (0.66) FFAR1
SCHEMBL2502272 0.89 FFAR1 (0.82) FFAR1
SCHEMBL12220643 0.89 FFAR1 (0.82) FFAR1
SCHEMBL2499362 0.89 FFAR1 (0.82) FFAR1
SCHEMBL13882377 0.89 FFAR1 (0.63) FFAR1
SCHEMBL2506445 0.83 FFAR1 (0.73) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030354-B2 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes AMGEN INC. (US) 2011-10-04 US disclosed