SCHEMBL25065360

SCHEMBL25065360

CC(C)C1CC(F)CN(c2cnccn2)C1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 2/20 0.39
KDM4E B2RXH2 5/20 0.37
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GPR119 Q8TDV5 2/20 0.34
RXFP1 Q9HBX9 1/20 0.33
TACR1 P25103 1/20 0.33
DPP4 P27487 2/20 0.33
DPP8 Q6V1X1 2/20 0.33
DPP7 Q9UHL4 2/20 0.33
VNN1 O95497 1/20 0.33
DPP9 Q86TI2 1/20 0.33
KMT2A Q03164 1/20 0.33
SORD Q00796 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357440 0.81 GRM1 (0.44) GRM1KDM4ELMNAL3MBTL1GPR119
SCHEMBL12988997 0.78 KDM4E (0.49) GRM1KDM4ELMNAL3MBTL1ALDH1A1
SCHEMBL23497613 0.78 PIM1 (0.43) GRM1KDM4EDPP4DPP8DPP7
SCHEMBL23497906 0.78 PIM1 (0.43) GRM1KDM4EDPP4DPP8DPP7
SCHEMBL25065358 0.76 CHRNB2 (0.49) DPP4DPP8DPP7DPP9
SCHEMBL25065356 0.75 KMT2A (0.46) KDM4EKMT2A
SCHEMBL12988347 0.74 KDM4E (0.55) KDM4ELMNAL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL23498046 0.71 PIM1 (0.39) GRM1KDM4EDPP4DPP8DPP7
SCHEMBL13703142 0.71 KDM4E (0.46) GRM1KDM4ELMNAL3MBTL1GPR119
SCHEMBL25065330 0.70 CHRNB2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055741-A1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2023-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230055741-A1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS GRM1 2194/4885KDM4E 2817/4885LMNA 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.