SCHEMBL25067211

SCHEMBL25067211

CCC(=O)Cn1cnc2ccc(N3CCN(C)CC3)cc2c1=O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 18/20 0.55
MAPK14 Q16539 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18130455 0.78 ENPP2 (0.67) ENPP2
SCHEMBL19833117 0.77 ENPP2 (0.67) ENPP2
SCHEMBL18130544 0.75 ENPP2 (0.67) ENPP2
SCHEMBL296197 0.75 ENPP2 (0.49) ENPP2
SCHEMBL30202377 0.75 ENPP2 (0.49) ENPP2
SCHEMBL23489657 0.74 ENPP2 (0.54) ENPP2
Hydrochloric Acid SCHEMBL1921111 0.74 ENPP2 (0.49) ENPP2
SCHEMBL11982379 0.74 SMN1; SMN2 (0.66)
SCHEMBL28403570 0.72 SMN1; SMN2 (0.56)
SCHEMBL18130550 0.72 ENPP2 (1.00) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230057847-A1 GLP2 RECEPTOR AGONISTS AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2023-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230057847-A1 GLP2 RECEPTOR AGONISTS AND METHODS OF USE GLP1R, GIPR, GRPR ENPP2 94/4885MAPK14 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.