Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24039270 | 0.99 | MAPT (0.39) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL24039678 | 0.99 | MAPT (0.39) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL22987010 | 0.96 | KMT2A (0.37) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL24039360 | 0.95 | KMT2A (0.37) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL24039207 | 0.95 | AHR (0.39) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL24039245 | 0.95 | KMT2A (0.37) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL24039567 | 0.94 | PLA2G2A (0.37) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23437499 | 0.94 | PLA2G2A (0.40) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL24039126 | 0.94 | PLA2G2A (0.37) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23437069 | 0.94 | PLA2G2A (0.40) | MAPTKMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230108986-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-04-06 | — | — | US | disclosed |
| US-20230059210-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |