Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 6/20 | 0.75 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.43 |
| ▸ | LCK | P06239 | 4/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | WHR1 | P49842 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25069001 | 1.00 | ITK (0.75) | ITKAURKBLCKSSTR5RORC | |
| SCHEMBL23409058 | 0.91 | ITK (0.76) | ITKAURKBLCKSSTR5RORC | |
| SCHEMBL25069003 | 0.91 | ITK (0.76) | ITKAURKBLCKSSTR5RORC | |
| SCHEMBL20767484 | 0.86 | ITK (1.00) | ITKAURKBLCKRORCDHODH | |
| SCHEMBL20767487 | 0.86 | ITK (1.00) | ITKAURKBLCKRORCDHODH | |
| SCHEMBL20767486 | 0.86 | ITK (1.00) | ITKAURKBLCKRORCDHODH | |
| SCHEMBL2398855 | 0.85 | ITK (0.70) | ITKAURKBLCKSSTR5POLB | |
| SCHEMBL2397738 | 0.85 | ITK (0.70) | ITKAURKBLCKSSTR5POLB | |
| SCHEMBL2395070 | 0.85 | ITK (0.70) | ITKAURKBLCKSSTR5POLB | |
| SCHEMBL2397749 | 0.85 | ITK (0.70) | ITKAURKBLCKSSTR5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | ITK 1618/4885AURKB 2422/4885LCK 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.