Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25070615 | 0.89 | ESR1 (0.37) | ESR1ESR2APP | |
| SCHEMBL25070414 | 0.89 | APP (0.35) | ESR1ESR2APPPDK2TERT | |
| SCHEMBL25070323 | 0.85 | ESR1 (0.36) | ESR1ESR2APP | |
| SCHEMBL25070593 | 0.81 | ESR1 (0.35) | ESR1ESR2ALDH1A1KDM4ELMNA | |
| SCHEMBL25070564 | 0.80 | KDM4E (0.31) | APPALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL25070495 | 0.80 | APP (0.56) | ESR1ESR2APPALDH1A1KDM4E | |
| SCHEMBL19369162 | 0.80 | ESR2 (0.46) | ESR1ESR2 | |
| SCHEMBL26500096 | 0.80 | HSD17B1 (0.42) | ESR1ESR2 | |
| SCHEMBL20806237 | 0.79 | ESR2 (0.45) | ESR1ESR2 | |
| SCHEMBL20806065 | 0.77 | CYP1A1 (0.41) | ESR1ESR2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |