Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 19/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 10/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551474 | 1.00 | ERN1 (0.48) | ERN1MAPK10KDRTEK | |
| SCHEMBL21908731 | 1.00 | ERN1 (0.48) | ERN1MAPK10KDRTEK | |
| SCHEMBL21909261 | 0.95 | ERN1 (0.46) | ERN1MAPK10 | |
| SCHEMBL25071801 | 0.95 | ERN1 (0.46) | ERN1MAPK10 | |
| SCHEMBL28554822 | 0.95 | ERN1 (0.46) | ERN1MAPK10 | |
| SCHEMBL28555901 | 0.92 | ERN1 (0.49) | ERN1MAPK10 | |
| SCHEMBL25071795 | 0.92 | ERN1 (0.49) | ERN1MAPK10 | |
| SCHEMBL25071948 | 0.86 | ERN1 (0.57) | ERN1MAPK10 | |
| SCHEMBL21811392 | 0.86 | ERN1 (0.57) | ERN1MAPK10 | |
| SCHEMBL30143179 | 0.86 | ERN1 (0.57) | ERN1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-02-23 | — | — | US | disclosed |
| CN-112739420-A | Phenoxy-pyridyl-pyrimidine compounds and methods of use | 基因泰克公司 | 2021-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | XBP1, ERN1, ESR2 | ERN1 2/4885MAPK10 1353/4885KDR 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.