Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2507428 | 0.87 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL9981362 | 0.86 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL2507429 | 0.82 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL9982401 | 0.81 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL2506464 | 0.77 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL2509101 | 0.75 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL2502778 | 0.75 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL9981168 | 0.75 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL2505626 | 0.74 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL2503861 | 0.74 | KCNH2 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245259-A1 | 5-Amino-2-(1-Hydroxy-Ethyl)-Tetrahydropyran Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245259-A1 | 5-Amino-2-(1-Hydroxy-Ethyl)-Tetrahydropyran Derivatives | CD2, CD22, DRD3 | KCNH2 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.