SCHEMBL25075019

SCHEMBL25075019

CC(Br)Cc1ccc2c(c1)OCO2

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.70
SLC6A4 P31645 3/20 0.70
SLC6A2 P23975 2/20 0.70
SLC6A3 Q01959 2/20 0.70
CYP2D6 P10635 2/20 0.66
CYP3A4 P08684 2/20 0.60
NPSR1 Q6W5P4 1/20 0.59
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
ATM Q13315 1/20 0.54
CMA1 P23946 1/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30942654 1.00 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL104467 0.85 TAAR1 (0.74) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Machilin A SCHEMBL10343221 0.85 TAAR1 (0.74) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Machilin A SCHEMBL31237868 0.85 TAAR1 (0.74) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Machilin A SCHEMBL30678762 0.85 TAAR1 (0.74) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL393456 0.82 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL9150773 0.82 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL20402802 0.82 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL21791708 0.82 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL4170645 0.82 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108931646-B Test strip for detecting safrole and preparation method and application thereof 中国烟草总公司郑州烟草研究院 2021-04-27 CN claimed
CN-108689985-B Preparation method and application of safrole hapten and antigen 中国烟草总公司郑州烟草研究院 2021-01-12 CN claimed
CN-108844932-B Time-resolved fluorescence immunochromatographic test strip for detecting safrole as well as preparation method and application thereof 中国烟草总公司郑州烟草研究院 2020-10-30 CN claimed
CN-118206417-A Cobalt catalytic dehalogenation deuteration method 中国科学院大连化学物理研究所 2024-06-18 CN disclosed
WO-2023019298-A1 IMPROVED METHOD OF SYNTHESIS OF 1-(3',4'-METHYLENE DIOXYPHENYL)-2-(METHYLAMINO) PROPANE (MDMA) MIND MEDICINE AUSTRALIA LIMITED (AU) 2023-02-23 WO disclosed
CN-109813922-B Enzyme linked immunosorbent assay kit for detecting chlorpromazine and application thereof 北京勤邦生物技术有限公司 2023-01-20 CN disclosed
CN-108931646-B Test strip for detecting safrole and preparation method and application thereof 中国烟草总公司郑州烟草研究院 2021-04-27 CN disclosed
CN-108709992-B Enzyme linked immunosorbent assay kit for detecting safrole and application thereof 中国烟草总公司郑州烟草研究院 2021-03-09 CN disclosed
CN-108709992-B Enzyme linked immunosorbent assay kit for detecting safrole and application thereof 中国烟草总公司郑州烟草研究院 2021-03-09 CN disclosed
CN-108689985-B Preparation method and application of safrole hapten and antigen 中国烟草总公司郑州烟草研究院 2021-01-12 CN disclosed
CN-108844932-B Time-resolved fluorescence immunochromatographic test strip for detecting safrole as well as preparation method and application thereof 中国烟草总公司郑州烟草研究院 2020-10-30 CN disclosed
CN-108844932-B Time-resolved fluorescence immunochromatographic test strip for detecting safrole as well as preparation method and application thereof 中国烟草总公司郑州烟草研究院 2020-10-30 CN disclosed