Tenamfetamine

Tenamfetamine

SCHEMBL393456

CC(N)Cc1ccc2c(c1)OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 1.00
SLC6A4 P31645 3/20 1.00
SLC6A2 P23975 2/20 1.00
SLC6A3 Q01959 2/20 1.00
CYP2D6 P10635 2/20 0.66
CYP3A4 P08684 2/20 0.60
NPSR1 Q6W5P4 1/20 0.59
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tenamfetamine SCHEMBL9361151 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL29392330 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30242630 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30904507 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL15162053 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30242515 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30203543 0.98 TAAR1 (0.97) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30401290 0.98 TAAR1 (0.97) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL5305879 0.98 TAAR1 (0.97) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL22885190 0.89 TAAR1 (0.81) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747639-A2 BETA-GALACTOSIDASE ENZYME-BASED IMMUNOASSAY Abbott Diagnostics Scarborough, Inc. (US) 2026-05-27 EP claimed
CN-122076506-A Composite catalyst for synthesizing berberine intermediate piperonylethylamine and preparation method thereof 2026-05-26 CN claimed
EP-4727538-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2026-04-22 EP claimed
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2026-04-02 US claimed
EP-4358962-B1 TREATMENT FOR AUTOIMMUNE DISEASES COMPRISING NALTREXONE OR A METABOLITE OR ANALOG THEREOF, A CANNABINOID AND A 5-HT RECEPTOR AGONIST LDN PHARMA LTD (GB) 2026-02-04 EP claimed
EP-4673125-A1 R-MDMA FOR TREATMENT OF PAIN Mind Medicine, Inc. (US) 2026-01-07 EP claimed
US-12514883-B2 Compositions and methods for modulating lipid and steroid metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
EP-4662205-A1 DERIVATIVES, IMMUNOGENS, AND ANTIBODIES AND USE OF THE SAME IN DETECTION OF ECSTASY-CLASS COMPOUNDS Siemens Healthcare Diagnostics, Inc. (US) 2025-12-17 EP claimed
US-12429484-B2 Homogeneous enzyme immunoassay for keratinized structures PSYCHEMEDICS CORPORATION (US) 2025-09-30 US claimed
EP-4615828-A2 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EmpathBio, Inc. (US) 2025-09-17 EP claimed
US-20050130243-A1 Assay for entactogens SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-06-16 US claimed
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists ELAN PHARMACEUTICALS, INC. 2005-01-27 US claimed
WO-2004103283-A2 COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CENTRAL NERVOUS SYSTEM STIMULANT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE PHARMACIA CORPORATION (US) 2004-12-02 WO claimed
US-6669937-B2 A monoclonal antibody that specifically recognizes a stimulant or hallucinogenic drug of abuse or a metabolite, selected from d-methamphetamine, d-amphetamine, 3,4-methylenedioxymethamphetamine or derivatives THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2003-12-30 US claimed
US-20030119083-A1 Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-06-26 US claimed
WO-2003052426-A1 A METHOD FOR THE DETECTION OF COMPOUNDS COMPRISING METHYLENEDIOXYPHENYL AND TESTING KIT FOR THE SAME GLATTSTEIN ORA (IL) 2003-06-26 WO claimed
US-20020013372-A1 Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors PFIZER PRODUCTS INC. 2002-01-31 US claimed
US-20010051158-A1 Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs BIOVENTURES, LLC 2001-12-13 US claimed
EP-1134290-A2 Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors Pfizer Products Inc. (US) 2001-09-19 EP claimed
US-4120976-A Treatments for arthritis and cast dermatitis HOSICK THOMAS A 1978-10-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists BDKRB1, BDKRB2, BRS3 TAAR1 307/4885SLC6A4 2641/4885SLC6A2 2937/4885
US-20050130243-A1 Assay for entactogens HTR3C, COMT, PNMT TAAR1 336/4885SLC6A4 370/4885SLC6A2 966/4885
US-20030119083-A1 Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs PNMT, EPHA5, EPHB1 TAAR1 116/4885SLC6A4 449/4885SLC6A2 119/4885
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness QPCT, SLC38A7, QPCTL TAAR1 3179/4885SLC6A4 440/4885SLC6A2 362/4885
US-20010051158-A1 Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs PNMT, EPHA5, EPHB1 TAAR1 106/4885SLC6A4 441/4885SLC6A2 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.