Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14466277 | 0.79 | — | — | |
| SCHEMBL7154654 | 0.77 | — | — | |
| SCHEMBL9474699 | 0.72 | NQO1 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL24945004 | 0.71 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL16608338 | 0.71 | — | — | |
| SCHEMBL10405288 | 0.70 | — | — | |
| SCHEMBL968737 | 0.70 | — | — | |
| SCHEMBL965496 | 0.70 | CA1 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20778903 | 0.69 | ALOX15 (0.37) | — | |
| SCHEMBL1097806 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020479-A1 | PARP7 INHIBITOR AND APPLICATION THEREOF | 重庆华森制药股份有限公司 | 2023-02-23 | — | — | WO | disclosed |