Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 5/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054715 | 1.00 | RORC (0.51) | RORCTACR1NR1H2NR1H3RXRA | |
| SCHEMBL31703732 | 1.00 | RORC (0.51) | RORCTACR1NR1H2NR1H3RXRA | |
| SCHEMBL31228445 | 0.88 | RORC (0.48) | RORCTACR1NR1H2NR1H3HTRA1 | |
| SCHEMBL25208441 | 0.88 | RORC (0.48) | RORCTACR1NR1H2NR1H3 | |
| SCHEMBL14343619 | 0.86 | RORC (0.46) | RORCTACR1NR1H2NR1H3GPR119 | |
| SCHEMBL15185071 | 0.86 | RORC (0.46) | RORCTACR1NR1H2NR1H3GPR119 | |
| SCHEMBL1595217 | 0.86 | RORC (0.46) | RORCTACR1NR1H2NR1H3GPR119 | |
| SCHEMBL4198304 | 0.86 | RORC (0.46) | RORCTACR1NR1H2NR1H3GPR119 | |
| SCHEMBL2299757 | 0.86 | RORC (0.46) | RORCTACR1NR1H2NR1H3GPR119 | |
| SCHEMBL830155 | 0.86 | RORC (0.46) | RORCTACR1NR1H2NR1H3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023287-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS SEROTONIN (5-HT) 5-HT2A AND 5-HT2C RECEPTOR POSITIVE ALLOSTERIC MODULATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-02-23 | — | — | WO | disclosed |