SCHEMBL25077162

CCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1[C@@]2(C)O[C@@H](c3ccc4c(N)ncnn34)[C@H](O)[C@@]12O)Oc1ccc(C#N)nc1

nearest known ligand 0.39

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	POLRMT	O00411	1/20	0.35

▸	AKT1	P31749	6/20	0.33

▸	AKT2	P31751	5/20	0.33

▸	AKT3	Q9Y243	5/20	0.33

▸	PIK3R1	P27986	4/20	0.33

▸	PIK3CA	P42336	4/20	0.33

▸	PLCG2	P16885	1/20	0.32

▸	GAB1	Q13480	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25077075	0.92	POLRMT (0.35)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773860	0.91	POLRMT (0.34)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773864	0.91	POLRMT (0.34)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25077601	0.89	POLRMT (0.35)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773875	0.89	POLRMT (0.34)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25077021	0.88	POLRMT (0.43)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25077250	0.88	POLRMT (0.43)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25077032	0.88	POLRMT (0.43)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773369	0.87	POLRMT (0.34)	POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25774275	0.86	POLRMT (0.35)	POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023023527-A1	PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME	GILEAD SCIENCES, INC. (US)	2023-02-23	—	—	WO	disclosed